教員紹介

SDGsへの取り組み

最終学歴

星薬科大学大学院　薬学研究科　博士課程前期修了 (植物薬品化学専攻）

取得学位

博士（薬学） (星薬科大学)

所属学会

日本薬学会、日本生薬学会

現在の専門分野

生薬学、植物薬品化学、生薬薬理、生薬・生薬製剤分析

現在の研究課題

●心血管系疾患治療を目指した天然物由来成分の研究
●漢方・生薬成分の体内動態に関する研究
●漢方・生薬の成分研究と品質評価への応用

主要研究業績

●ラット血管平滑筋弛緩作用を示す天然由来成分の構造と薬理．
●ヒト血小板の凝集抑制作用をもつ生薬・植物成分の探索と薬理研究．
●生薬成分の変動と品質評価に関する研究
●漢方・生薬製剤の試験法開発および品質評価研究と品質評価への応用

最近の研究業績

1. Vasorelaxant effects of Acer nikoense extract and isolated coumarinolignans on rat aortic rings. Iizuka Toru; Nagumo Seiji; Yotsumoto Hideomi; Moriyama Hiroyoshi; Nagai Masahiro Biological & pharmaceutical bulletin (2007), 30(6), 1164-6.

2. Inhibitory effects of methyl brevifolincarboxylate isolated from Phyllanthus niruri L. on platelet aggregation. Iizuka Toru; Nagai, Masahiro; Taniguchi, Akemi; Moriyama, Hiroyoshi; Hoshi, Keiko. Biological & Pharmaceutical Bulletin (2007), 30(2), 382-384.

3. Vasorelaxant activity of cyclic peptide, cyclosquamosin B, from Annona squamosa. Morita, Hiroshi; Iizuka Toru; Choo, Chee-Yan; Chan, Kit-Lam; Takeya, Koichi; Kobayashi, Jun'ichi. Bioorganic & Medicinal Chemistry Letters (2006), 16(17), 4609-4611.

4. Relaxing effects of Phellinus gilvus extract and purified eburicoic acid on rat aortic rings. Hosoe, Tomoo; Iizuka Toru; Chiba, Yoshihiko; Itabashi, Takeshi; Morita, Hiroshi; Ishizaki, Takayuki; Kawai, Ken-ichi. Journal of Natural Medicines (Tokyo) (2006), 60(2), 130-134.

5. Vasorelaxant effects of methyl brevifolincarboxylate from the leaves of Phyllanthus niruri. Iizuka Toru; Moriyama, Hiroyoshi; Nagai, Masahiro. Biological Pharmaceutical Bulletin (2006), 29(1), 177-179.

6. Antiplatelet aggregatory effects of the constituents isolated from the flower of Carthamus tinctorius. Iizuka Toru; Nagai, Masahiro; Moriyama, Hiroyoshi; Taniguchi, Akemi; Hoshi, Keiko. Natural Medicines (Tokyo, Japan) (2005), 59(5), 241-244.

7. 4-Benzyl-3-phenyl-5H-furan-2-one, a vasodilator isolated from Malbranchea filamentosa IFM 41300. Hosoe, Tomoo; Iizuka Toru; Komai, Shin-ichirou; Wakana, Daigo; Itabashi, Takeshi; Nozawa, Koohei; Fukushima, Kazutaka; Kawai, Ken-ichi Phytochemistry (Elsevier) (2005), 66(23), 2776-2779.

8. 連翹より得られたForsythiasideの血管平滑筋弛緩作用. 飯塚 徹, 永井 正博. 薬学雑誌 (2005),125(2), 219-224.

9. N-カフェオイルアミノ酸類の血管平滑筋弛緩作用. 飯塚　徹, 船山 浩子, 草野 源次郎, 永井 正博. 薬学雑誌 (2003), 123(11), 963-971.

10. Adenine, an inhibitor of platelet aggregation, from the leaves of Cassia alata. Moriyama, Hiroyoshi; Iizuka Toru; Nagai, Masahiro; Hoshi, Keiko. Biological & Pharmaceutical Bulletin (2003), 26(9), 1361-1364.

11. HPLC quantification of kaempferol-3-O-gentiobioside in Cassia alata. Moriyama, Hiroyoshi; Iizuka Toru; Nagai, Masahiro; Murata, Yoshimi. Fitoterapia (2003), 74(5), 425-430.

12. A stabilized flavonoid glycoside in heat-treated Cassia alata leaves and its structural elucidation. Moriyama, Hiroyoshi; Iizuka Toru; Nagai, Masahiro. Yakugaku Zasshi (2001), 121(11), 817-820.